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The following are the supplementary
2018-11-06
The following are the supplementary data related to this article. Acknowledgment This work was supported by the Ministry of Science and Technology 973 program of China (2011CB504402, 2012CB966802 and 2012CB966304), and the \"Strategic Priority Research Program\" of the Chinese Academy of Science
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To investigate whether PD derived
2018-11-06
To investigate whether PD-derived HSCs exist in other mammals, we analyzed the resident cells in the peritoneal cavity of C57BL/6 mice without any prior treatment. We found that there was a higher ratio (0.51±0.04%) of Lin−/Sca1+/c-kit+ population in the mouse peritoneal cavity than in bone marrow (
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The importance of the finding
2018-11-06
The importance of the finding that the prostaglandin pathway is selectively downregulated by MSX2, but not MSX1, is 2-fold; i) this functional disparity between MSX1 and MSX2 provides a mechanistic insight into a cellularization event during muscle dedifferentiation and ii) it also demonstrates that
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There were discrepancies between the
2018-11-06
There were discrepancies between the mRNA and protein levels of p63 and K12. It is known that the mRNA level does not always correlate with the protein level. In addition, protein expression rather than mRNA expression dictates the phenotype of the cells. A better correlation was found between the c
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Using the combination of a mitogen activated protein kinase
2018-11-06
Using the combination of a mitogen-activated protein kinase kinase (MEK) inhibitor, PD0325901 (PD03), and a glycogen synthase kinase 3 (GSK3) inhibitor, CHIR99021 (CHIR), which will hereafter be referred to as 2i, mouse ESCs (mESCs) are maintained in a ground state (Ying et al., 2008). CHIR activate
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Due to the major differences in phenotype between human and
2018-11-05
Due to the major differences in phenotype between human and murine GATA6 disease models, human pluripotent stem cells (PSCs) offer an alternative system for the in vitro study of GATA6. With recent developments in the genome-editing field, the use of clustered regularly interspaced short palindromic
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Here we identified and characterized MM cell subpopulations
2018-11-05
Here, we identified and characterized MM cell subpopulations in vitro based on their increased endogenous expression of SOX2 and OCT4 driving a reporter (EGFP) (Hotta et al., 2009; Tang et al., 2015). We demonstrate these angiotensin receptor blockers to have different properties with respect to ch
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When it comes to the development of statistical
2018-11-05
When it comes to the development of statistical radio engineering and radiophysics, Kotel\'nikov should be given credit where credit is due; we should point out, for historical accuracy, that in his monograph [2] he obtained, among other calculations, an example of a canonical decomposition, even th
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Thus the calculated Navier Stokes equations for an
2018-11-05
Thus, the calculated Navier–Stokes equations for an incompressible conducting fluid which include the density of the EM field force as the driving force can be expressed in the following way in differential form: Here μ is the effective viscosity, defined as the sum of the laminar and the turbule
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There are several limitations that should be considered when
2018-11-05
There are several limitations that should be considered when interpreting the results of this review. First, given the search strategy, we were unable to identify unpublished studies or studies that were not published in indexed journals. Studies in languages other than English were also not include
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To our knowledge there is no research investigating whether
2018-11-05
To our knowledge there is no research investigating whether the association between SRH and mortality differs across regions in the United States. Yet the question of regional variation in the mortality predictive validity of SRH is a central one. If the relationship between SRH and mortality varies
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As shown in Fig the
2018-11-05
As shown in Fig. 1, the proportion of the state budget spent on health care increased by 50% from 14.1% to 21.3% over the study period. The largest part of this spending was for Medicaid and other medical benefit payments, 77% of the total in FY2014. Other significant components were for prison heal
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br Materials and methods br Results and discussion br
2018-11-05
Materials and methods Results and discussion Study of the adsorption equilibrium Conclusions It was shown that the PAD polystyrenic resin can be successfully utilized as an adsorbent for the removal of benzene, toluene, ethylbenzene and isomers of xylene from wastewater. The equilibrium
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One of the most important
2018-11-05
One of the most important ways that Mo can be concentrated and fractionated from Cu is through the oxidation–reduction cycle during chemical weathering on the surface of the Earth. During weathering, molybdenum is readily oxidized to form water-soluble MoO42− in surface environments (Sun et al., 201
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Changes in FA in relation to changes in RD
2018-11-05
Changes in FA in relation to changes in RD and AD suggest that the greatest change in white matter microstructure was a reduction in RD that led to an increase in FA values. FA is an aggregate index of white matter integrity. It essentially reflects the prominence of diffusion along dexamethasone ac
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