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Preoperative imaging modalities such as contrast
2018-11-12
Preoperative imaging modalities, such as contrast-enhanced abdominal CT, facilitate diagnosis. Helical CT plays a crucial role in the diagnosis of intraluminal or exophytic tumors. The differential diagnosis of GI tract tumors should include fibromatosis, leiomyoma, schwannoma, inflammatory fibroid
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The scavenging abilities of compound and
2018-11-12
The scavenging abilities of compound 1 and fractions 2–6 on hydrogen peroxide need to be evaluated (Table 2) because even though it is not very reactive in human cells, hydrogen peroxide sometimes is toxic because it gives rise to the hydroxyl radical in cells [41]. Thus, antioxidants that remove hy
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br Experimental Procedures br Acknowledgments We are gratefu
2018-11-12
Experimental Procedures Acknowledgments We are grateful to Rosalind Gunby and Monica Autiero for careful reading and critical comments of the manuscript. We thank the Animal House and the Integrated Microscopy Facilities of IGB-Consiglio Nazionale delle Ricerche (CNR) and the Bioinformatic Cor
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In this study hPSC derived
2018-11-12
In this study hPSC-derived bfCNs were generated via an expandable NSC intermediate, which maintained the desired basal forebrain progenitor phenotype, and neurogenic capacity even after long-term expansion in culture. This scalability is a required feature of any cell type to be used in regenerative
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br Materials and methods br Results br
2018-11-12
Materials and methods Results Discussion Conclusion Author contributions Acknowledgments This study was supported by a grant from the Innovative Research Institute for Cell Therapy (A062260) and supported by the a grant of the Korea Health Technology R&D Project through the Korea H
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We sought to determine whether T cell derived iPSCs TiPSCs
2018-11-09
We sought to determine whether T cell-derived iPSCs (TiPSCs) could be used to analyze neurological diseases. Several issues regarding the utilization of TiPSCs in neurological studies remain unresolved. First, previous studies indicated that each iPSC clone retains an epigenetic memory relating to t
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We further confirm in human cells that inhibition of
2018-11-09
We further confirm in human CX4945 that inhibition of specifically canonical Wnt signaling following mesoderm induction is both necessary and sufficient for subsequent efficient cardiomyocyte differentiation (Figure 4H). Experimental activation of noncanonical Wnt/JNK signaling has been shown in a v
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Although the mechanisms of in vitro postovulatory
2018-11-09
Although the mechanisms of in vitro postovulatory aging and in vivo reproductive aging differ, there are some remarkable cytological similarities relevant to human reproduction. It has been reported that aging of human and mouse oocytes can result in disorganization of the spindle and defects in chr
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TSC haploinsufficient astrocytes presented a high proliferat
2018-11-09
TSC haploinsufficient astrocytes presented a high proliferation rate and an increased saturation density when compared with WT astrocytes. Similarly, the conditional disruption of TSC1 in astrocytes using a human GFAP-Cre system was shown to produce mice that presented with astrocytosis (Han and Sah
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However there are still some challenges
2018-11-09
However, there are still some challenges that need to be addressed in order for our findings to be developed as an effective treatment for autoimmunity prevention. First, although islet function was preserved in the EV-treated mice, decreased β cell mass in association with insulitis was still obser
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x y is a polynomial
2018-11-09
(x, y) is a polynomial of a finite degree k, and S(x, y) is an arbitrary harmonic function,. In order to construct spectrographic media, we need homogeneous polynomials, and they can be expressed as a sum of terms . Then let us put and calculate Δg: It is clear that the polynomial with a degr
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The spectra for different collision centralities are
2018-11-09
The spectra for different collision centralities are multiplied by the scaling coefficients: 102 (1), 101 (2), 100 (3), 10–1(4), 10–2 (5), 10–3(6). Vertical bars mark the statistical errors, boxes mark the systematic measurement errors. The nuclear modification factors for φ-mesons in Pb+Pb collisi
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Furthermore such classification criteria that select a highl
2018-11-09
Furthermore, such classification criteria that select a highly specific sub-population of SS participants (those with 2 out of 3 objective signs - focus score≥1, positive serology, and ocular staining score≥3) (Shiboski et al., 2012) could challenge external validity. Therefore, clinical trial resul
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mecamylamine In conclusion the number of tumours tumour size
2018-11-09
In conclusion, the number of tumours, tumour size, BCG instillation, and intravesical instillation of chemotherapy were found to be independent predictors for time to recurrence after TUR-Bt in Japanese patients with NMIBC. Our novel, simple, and prognostic classification may not only predict the re
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br Numerous studies have reported H the first discovered
2018-11-09
Numerous studies have reported H19, the first discovered long non-coding RNA (lncRNA), to have key regulatory functions in tumor development and progression (). This paternally imprinted gene is located close to the telomeric region of chromosome 11p15.5 that frequently harbors genetic alterations
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