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What lies ahead Clearly the extremely ambitious
2019-04-22
What lies ahead? Clearly the extremely ambitious goals and targets set by the UNCoLSC have not been reached, and challenges must be overcome. While the current evaluation highlights several challenges and strategies for action, a clear process in moving forward would be to link this bottleneck analy
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Introduction The hippocampus is a critical
2019-04-22
Introduction The hippocampus is a critical brain region for episodic memory formation in rodents and humans [1]. Hippocampal neurons, especially CA1 neurons, are highly vulnerable to ischemic injury [2], and failure of hippocampal function causes memory impairment and reduced cognitive ability [3,4
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In conclusion we observed that the rate of carbapenem
2019-04-22
In conclusion, we observed that the rate of carbapenem-resistant A. baumannii was high among burn patients. In addition, the most effective drugs against A. baumannii in vitro were colistin and polymyxin B. Since resistant isolates only had blaOXA-23-like and blaOXA-24-like, it seems that carbapenem
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CaMKII phosphorylation of L type Ca channels
2019-04-22
CaMKII phosphorylation of L-type Ca2+channels alters channel gating by increasing open probability. CaMKII increases the window current of ICa-L, increasing the probability of the channels reopening during phase 2 Exendin-3 (9-39) amide and predisposing to early afterdepolarizations. Recently ident
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Introduction Several types of cancers
2019-04-22
Introduction Several types of cancers, including those originating in the breast, prostate, and lung, have a propensity to metastasize to the bones [1,2]. Bone metastases severely impair skeletal metabolism, and result in important clinical sequelae, such as excruciating chronic bone pain and the s
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br Desde su t tulo
2019-04-22
Desde su título original y su actual portada, en franca coincidencia entre la lectura y el viaje, este libro nos anuncia y nos invita phosphatidylinositol 4-kinase emprender varios recorridos insólitos. El primero signado por el pasado, cuando, en efecto, para ir a Europa desde Santiago de Chile h
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The approach used of estimating
2019-04-22
The approach used, of estimating effectiveness relative to a matched counterfactual, can be regarded as an attempt to reach the ideal estimation of relative risk, namely the comparison of a population to itself with the exposure removed. However, it is not possible to know exactly what would have ha
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br In mid close to
2019-04-22
In mid-2015, close to the finish line of the Millennium Development Goals (MDGs), Tanzania has reason to be proud. As Hoviyeh Afnan-Holmes and colleagues note in their Countdown to 2015 case study, Tanzania is on track to achieve MDG4: a two-thirds hematopoietic stem cells in child mortality. The
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En segundo lugar el buen vivir
2019-04-22
En segundo lugar, el buen vivir, siguiendo el planteamiento original de la conaie de una crítica bax pathway la economía del mercado, plantea como uno de sus ejes principales la creación de un sistema económico social y solidario que reconoce al ser humano como sujeto y fin que “tiene por objetivo g
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En el segundo caso la Espa a republicana se constituye
2019-04-22
En el segundo caso, la España republicana se constituye como un espejo quebrado, aquello destruido, perdido y que es mejor olvidar para atender la historia urgente y presente del territorio latinoamericano, de muestra vale el ejemplo citado que refiere Calcium Ionophore I la importancia de centrar l
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Prior case reports have described hematological remission in
2019-04-22
Prior case reports have described hematological remission in patients with myelofibrosis during treatment with bisphosphonates, but a phase II study investigating the effects of zoledronic ABT-737 on patients with myelofibrosis showed responses in only 1 of 16 patients[13]. In conclusion, we report
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ZIKV is a flavivirus related to dengue virus DENV and
2019-04-22
ZIKV is a flavivirus related to dengue virus (DENV) and historically has been transmitted by the same mosquito species, (). There is no available treatment or vaccine so disease control is limited to the management of mosquitoes which currently relies on either insecticides or the destruction of lar
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Bernardo Ar valo de Le n
2019-04-20
Bernardo Arévalo de León señala que en Guatemala la dsn no alcanzó el nivel de desarrollo conceptual que tuvo en otros países como Chile, Brasil y Argentina. Del mismo modo, el general Héctor Alejandro Gramajo Morales, un teórico de la dsn en Guatemala, indicó que si bien el concepto de seguridad na
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mitoxantrone br Introduction Multiple signal transduction pa
2019-04-20
Introduction Multiple signal transduction pathways in normal and malignant mitoxantrone converge on Bcl-2 family proteins, which stand at the crossroads between cell survival and apoptosis. The seminal event in the intrinsic pathway of apoptosis is mitochondrial outer membrane permeabilization (M
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In the present study the TACT measurement scores by
2019-04-20
In the present study, the TACT measurement scores by EPS and TDI among women aged 20–30 were statistically and borderline significantly lower than in those aged 30–40. Similarly, men aged 20–30 years had lower scores than those aged 30–40. However, non-significant statistical differences were observ
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