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Given that CE plays an essential
2020-08-05
Given that CE plays an essential role in schistosome invasion, its immunoreactivity and protective potential is of significant interest. The native form of SmCE was found to be poorly immunogenic in immunized mice. An earlier study found that sera from S. mansoni patients have shown the presence of
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apoptosis An important indication of the
2020-08-05
An important indication of the in vitro enzymatic 1(2)-hydrogenation of 3-ketosteroids was obtained with a cell-free extract preparation of a Δ1-KSTD from B. sphaericus ATCC 7055. Incubation of ADD (9) with a fraction of the cell-free extract in the presence of 3H2O resulted in a small quantity of h
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br Acknowledgments The authors would like to
2020-08-05
Acknowledgments The authors would like to thank Dr. Yuan Shao and Chris Elly (La Jolla Institute for Allergy and Immunology) for providing the constructs of Cbl, Cbl-b and Cbl-b WA and Dr. Haining Huang (La Jolla Institute for Allergy and Immunology) for technique assistances. This work has been
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Cy3 hydrazide br Results br Discussion Protein phosphorylati
2020-08-05
Results Discussion Protein phosphorylation plays a particularly important role in translational control mechanisms. Phosphorylation of components of the translation machinery, e.g., eIF2α, eIF4B, eIF4E, eIF4G, or eEF2, is common to mechanisms regulating global translation (Dever, 2002, Raught
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Acute renal failure in cats can arise from
2020-08-05
Acute renal failure in cats can arise from numerous causes [34], [35], [36], [37], [38], [39], [40] and has a very poor prognosis [36], [41]. Many cats who survive to discharge are azotaemic and, as a result, are likely to have high morbidity and greatly-reduced lifespan, while a second “wave” of ap
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Due to intense biological alterations
2020-08-05
Due to intense biological alterations induced by various risk factors of obesity, the adipose tissue undergoes adaptations such as adipocyte hypertrophy superimposed with hyperplasia (Jo et al., 2009). In addition to these changes, the adipocytes experience a process of cellular differentiation the
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Similar to Bdnf acute administration of RG did no http
2020-08-05
Similar to Bdnf4, acute administration of RG108 did not alter gene expression of Gria1 and Hdac2, despite their relevance for the task. Gria1 belongs to the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic atp enzyme receptor (AMPAR) family that is known to be crucial for LTP and the strengthening o
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There are studies that evaluated the stability of
2020-08-05
There are studies that evaluated the stability of CMV DNA over different periods of time. A study that evaluated stability of EDTA plasma samples stored over a 21-day period at 4 °C found no significant change in the viral loads or any trend of continued DNA degradation [9]. Another study did not fi
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br Experimental Procedures br Author
2020-08-05
Experimental Procedures Author Contributions M.M. and M.T. designed and supervised the study. S.I. conducted the analysis on NOG-rd mice. H.-Y.T., M.F., and T.M. conducted and analyzed MEA. S.I., H.-Y.T., and M.M. performed 3D image analysis. N.K., T.K., M.G., and R.T. planned and established
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In addition to the receptor TGF also regulates the
2020-08-04
In addition to the receptor, TGF-β1 also regulates the DDR1 ligand meaning the type I collagen and the enzyme involved in its maturation (LOXL2). We previously demonstrated that an increase of type I collagen concentration is associated with the presence of more linear invadosomes in gnrh agonists (
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br Materials and methods br Results br Discussion br Acknowl
2020-08-04
Materials and methods Results Discussion Acknowledgements We thank P.J. Focia and Z. Wawrzak for support in data collection and S. Gomes for support in generating IL-34 mutant clones. X.H. is supported by the NIH grant 1R01GM078055. The Structural Biology Facility is supported by the R.H
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br Experimental Procedures br Author Contributions
2020-08-04
Experimental Procedures Author Contributions Acknowledgments Introduction Influenza virus, which belongs to family Orthomyxoviridae, replicates its single-stranded negative-sense genomic RNAs in the host nucleus. The viral genomic RNAs are then packed into viral ribonucleoproteins (vRNPs
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br Benign migratory glossitis BMG
2020-08-04
Benign migratory glossitis (BMG), also known as , is a common oral mucosal lesion that usually affects the dorsal and lateral surfaces of the tongue. BMG is characterized by erythematous areas, representing papillary atrophy, surrounded by a whitish peripheral zone. These areas vary widely in appe
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The lack of significant effects on serum and tissue choleste
2020-08-04
The lack of significant effects on serum and tissue cholesterol levels, or cholesterol and bile acid synthesis in Villin-Tgif1 fed a chow diet may also be due to a pathway termed transintestinal cholesterol efflux (TICE) [34]. Cholesterol is excreted by biliary secretion but can, at least in mice, a
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br Advent of SMEPT br SMEPT for localized
2020-08-04
Advent of SMEPT SMEPT for localized synthesis of nitric oxide Critical evaluation and outlook Examples discussed in this Phos-tag review present SMEPT as a methodology for localized drug synthesis – a unique opportunity for site specific therapeutic interventions using implantable biomater
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