• Introduction Traumatic brain injury TBI is a leading cause o

  2018-10-22

  

  Introduction Traumatic brain injury (TBI) is a leading cause of death and disability among children and young adults. It has limited treatment options. TBI survivors often suffer from severe disturbances regarding cognitive ability, memory, and neurological deficits. An unfavorable outcome rate con

• br Acknowledgement We gratefully acknowledge the

  2018-10-22

  

  Acknowledgement We gratefully acknowledge the Department of Food Science and Technology, Ferdowsi University of Mashhad for financial support of this work. Introduction Fungal polysaccharide, a kind of active organic compound, is found in the mycelium, fruiting bodies, and fermentation broth

• br Acknowledgements br Introduction Major research interests

  2018-10-22

  

  Acknowledgements Introduction Major research interests have been attributed to reactive oxygen species (ROS) and their likely involvement in human physiopathology from the health point over the last few decades. Oxidative stress, caused by an imbalance between antioxidant systems and the prod

• br Conclusion and future prospects The research

  2018-10-22

  

  Conclusion and future prospects The research on M. oleifera is yet to gain importance in India. It is essential that the nutrients of this wonder tree are exploited for a variety of purposes. M. oleifera has great anti-diabetic and anti-cancer properties. However, double blind researches are less

• The goals of the current study were to investigate

  2018-10-22

  

  The goals of the current study were to investigate the changes in anal sphincter pressure after IV or IM injection of MSCs in our previously established animal models. Our models (Salcedo et al., 2010; Zutshi et al., 2009a) allow measurement of anal sphincter pressure and EMG in vivo in a repeated,

• Introduction The stem cell niche is

  2018-10-22

  

  Introduction The stem cell niche is a unique microenvironment that maintains long-term repopulation of a specific tissue by undergoing self-renewal of stem ABT-263 and by producing progenies of increasingly differentiated cells. A large amount of knowledge concerning the regulation of stem cell sel

• In this study we have described methods for the

  2018-10-22

  

  In this study we have described methods for the selective isolation of primitive hMSCs that may prove advantageous both experimentally and therapeutically. The identification of the combination marker LTV makes it possible to prospectively isolate functional hMSCs directly from BM. Using these cells

• mth1 pathway To study the status of DNA

  2018-10-22

  

  To study the status of DNA methylation during cellular reprogramming, we have analyzed the gene expression and methylation profiles of somatic mth1 pathway from three different lineages, representative of different embryonic germ-layers, and the iPSCs derived from them, as well as control human ESCs

• br Results br Discussion br Experimental Procedures br Ackno

  2018-10-22

  

  Results Discussion Experimental Procedures Acknowledgments Introduction The transplantation of dopaminergic (DA) neurons represents one of the potential strategies for the treatment of Parkinson’s disease (PD), and human pluripotent stem lipid metabolism (PSCs) are expected to be a p

• Co culture of CDSCs with USSCs revealed regulation of osteo

  2018-10-22

  

  Co-culture of CDSCs with USSCs revealed regulation of osteo- and chondro-associated markers, from which BMP2, BMP4, PTHLH, ACAN and FOXF1 were upregulated and BSP, RUNX2, SOX9, TWIST1 and MSX2 were downregulated after co-culture (Supplementary Fig. 8). Many different transcription factors and regula

• We recently found that E cad function cannot

  2018-10-22

  

  We recently found that E-cad function cannot be replaced by N-cad during the formation of the trophectoderm, the first polarized epithelium formed during mammalian development. In the blastocyst, the E-cad extracellular domain provides a unique and indispensable survival signal by facilitating Igf1r

• In conclusion a D suspended MC rocker

  2018-10-20

  

  In conclusion, a 3D suspended MC rocker platform, similar to a wave bioreactor, that integrates both hESC expansion and CM differentiation has been developed and shown to be capable of producing the highest quantities of CMs to date (190.5±58.8×106 cTnT positive CM/production run; 31.75±9.74 cTnT po

• The following are the supplementary data related to this

  2018-10-20

  

  The following are the supplementary data related to this article. Acknowledgments This study was supported by the Korea Healthcare Technology R&D Project, Ministry of Health, Welfare, and Family Affairs, Republic of Korea (Grant no. A120262) and a 2012 grant (10172KFDA993) from the Korea Food &

• Even though substrate stiffness and tethering is mostly

  2018-10-20

  

  Even though substrate stiffness and tethering is mostly known to affect focal adhesions (Trappmann et al., 2012; Wen et al., 2014; Levental et al., 2009), increasing evidence suggests that it may also affect cadherin-mediated intercellular adhesion (Smutny and Yap, 2010; Ladoux et al., 2010). Substr

• The finding that MHC and myogenin expression does not change

  2018-10-20

  

  The finding that MHC and myogenin expression does not change upon ectopic Msx1 expression but decreases drastically upon Msx2 expression is another piece of evidence for the selective role of MSX2 in dedifferentiation. The previous two studies on MSX1 induction in myotubes did not characterize MHC l

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