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After immersion in bovine milk SG there was a significant
2018-10-25

After immersion in bovine milk (SG1) there was a significant increase in Ca/P ratio. This increase may be due to the Ca content in bovine milk. Also, there was a significant decrease in C level. The decrease in C and increase in Ca wt% reflect an increase in the enamel hardness and a decrease in its
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While we showed that endothelial cells and astrocytes contri
2018-10-24

While we showed that endothelial SCR7 and astrocytes contribute to the regulation in the neurogenic niche of the hippocampus, the role of pericytes is far less conclusive. For most time pericytes have received relatively little attention and only more recently their role in the context of regenerati
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br Conclusions The following are
2018-10-24

Conclusions The following are the supplementary data relate to this article. Disclosure of potential conflicts of interest Acknowledgments We thank Fondazione Roma for continuous support. We also acknowledge Prof. Mara Riminucci, Prof. Luca Pierelli, Dr. C. Murdoch, Dr. Paola Iudicone and
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In contrast to the normal cells the requirement for
2018-10-24

In contrast to the normal cells, the requirement for cell:cell contacts to promote survival was removed in the H7 and H14 adapted cells, implying the loss of niche dependence, as has also been reported elsewhere (Werbowetski-Ogilvie et al., 2009). Consequently, the functional significance of the obs
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br Experimental Procedures br Author Contributions
2018-10-24

Experimental Procedures Author Contributions Acknowledgments Introduction Induced pluripotent stem Mitiglinide Calcium (iPSCs) have similar properties as embryonic stem cells (ESCs), such as self-renewal and differentiation capacity (Park et al., 2008c; Takahashi and Yamanaka, 2006). Rep
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Monosynaptic tracing using modified rabies virus has
2018-10-24

Monosynaptic tracing using modified rabies virus has previously been successfully used to trace existing neuronal circuits in vivo (Wall et al., 2013; Watabe-Uchida et al., 2012) and also to map the integration of newborn neurons in the olfactory bulb and hippocampus (Deshpande et al., 2013; Vivar e
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br Results br Discussion Analysis of DNA damage foci
2018-10-24

Results Discussion Analysis of DNA-damage foci in CHK1i-treated EZ Cap Reagent AG led to the remarkable discovery that CHK1i allowed FA-deficient iPSCs to escape G2 arrest and undergo mitosis without repairing the DSBs that had evidently caused their arrest. A previous study indicates that DS
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The present study indicated that induction of glutamatergic
2018-10-24

The present study indicated that induction of glutamatergic markers by nucleotides involved the P2Y4-Gq signaling axis. Expression of the P2Y4 nucleotide receptor was transiently augmented in the course of neuronal differentiation of ESCs, which is coincident with the window of nucleotide-induced vG
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br Introduction The balance between hematopoietic stem
2018-10-24

Introduction The balance between hematopoietic stem cell (HSC) proliferation and quiescence is tightly regulated (He et al., 2009). Adult HSCs are usually quiescent, but their proliferation rates increase upon exposure to cytokines (Baldridge et al., 2010; Essers et al., 2009; Morrison et al., 19
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Among the epigenetic aberrations of iPSCs DNA methylation is
2018-10-24

Among the epigenetic aberrations of iPSCs, DNA methylation is of particular importance. Previous studies showed that unique de novo differentially methylated (DMR) or hydroxymethylated regions (hDMR) are present in iPSCs compared with hESCs (Lister et al., 2011; Wang et al., 2013). Furthermore, the
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Traditionally testing of hPSC lines for gross chromosomal ch
2018-10-24

Traditionally, testing of hPSC lines for gross chromosomal changes employed karyology by chromosome banding of metaphase nuciferine (Amps et al., 2011; Baker et al., 2007). Although karyotyping allows examination of the entire cell genome in a single assay, an often overlooked issue in evaluating h
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SAG Overall our data support the view
2018-10-24

Overall, our data support the view that the SEZ is a source of plasticity for the adult CC, and that oligodendroblasts could be a valid therapeutic tool for demyelinating diseases if their generation from wider parts of the SEZ could be stimulated, if their response could be sustained for long perio
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A complementary study confirms our findings that GATA is nec
2018-10-24

A complementary study confirms our findings that GATA6 is necessary for 10058-F4 specification as well as the decreased efficiency of β-like cell generation from the GATA6 PSC line (Shi et al., 2017). This other report did have one major discrepancy with our results; they did not see a defect in gl
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br Methods br Results In there were
2018-10-24

Methods Results In 1860 there were 1100 counties within the boundaries of states legally permitting slavery (Upper South: 621; Deep South: 479), and in 2010 these same states consisted of 1,347 counties or county equivalents (716 and 624 for the Upper and Deep South, respectively). Spatial int
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However after several decades of
2018-10-24

However, after several decades of globalisation and neoliberal economic policies, long-term employment contracts and a high level of job security have become less GSK1120212 on the labour market. Instead, precarious work, i.e. short-term contracts, involuntary part time employment, employment throug
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