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Several ongoing clinical trials are evaluating the feasibili
2018-11-13
Several ongoing clinical trials are evaluating the feasibility of combining chemotherapeutic nanomedicines with radiotherapy or small molecule drugs (such as gemcitabine). Pegylated liposomal doxorubicin has shown improved therapeutic efficacy when combined with radiotherapy in several animal studie
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Research was supported by Leukaemia Lymphoma Research UK
2018-11-13
Research was supported by Leukaemia Lymphoma Research UK (LLR Grant10016 to MFK, LLR Gordon Piller Studentship award Grant11043 to MFK, AK, DP), by an MRC-Imperial Confidence-in-Concept (ICiC) grant to MFK, and by the NIHR Biomedical Research Centre at Imperial College NHS Trust, London. Results
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Patients diagnosed with lung cancer have a
2018-11-13
Patients diagnosed with lung cancer have a 5year survival rate of thoracic Embelin toxicity is pneumonitis and pulmonary fibrosis which can be life threatening and can affect patients\' quality of life and treatment outcome (reviewed in Abratt and Morgan, 2002). Therefore assessment of response to t
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L pneumophila is a Gram negative facultative
2018-11-13
L. pneumophila is a Gram-negative facultative intracellular bacterium that multiplies in aquatic environments, especially in free-living protozoa and biofilms (Newton et al., 2010; Carratalà and Garcia-Vidal, 2010). Legionellosis is an acute pneumonia caused by inhalation of aerosols containing Legi
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By sorting and sequencing HBsAg memory
2018-11-13
By sorting and sequencing HBsAg+(memory) and PC+ cells, we were able to confirm that dna synthesis inhibitors specific to the vaccine caused the signatures we saw in the repertoire. Both the HBsAg+ and PC+ clusters had increased convergence, mutation, and size compared to the total repertoire, and t
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In summary we report the first Taiwanese patient with
2018-11-12
In summary, we report the first Taiwanese patient with recurrent mycetomatous S. apiospermum infection. The infection of the foot recurred twice after two surgical excisions plus oral itraconazole therapy, and was finally controlled by another surgical excision which was followed by a 4-month course
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Onychopapilloma is an uncommon benign neoplasm of the nail
2018-11-12
Onychopapilloma is an uncommon, benign neoplasm of the nail bed, first described by Baran and Perrin in 1995; the term onychopapilloma was coined in 2000. The clinical features of onychopapilloma are nonspecific. The most common clinical presentation is longitudinal erythronychia, but many other cl
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It is readily found that the
2018-11-12
It is readily found that the expectation and variance arewhere Γ() is the Gamma function. To ensure that the expectation equals one, we set the scale parameter for varying values of the Weibull modulus M. When M approaches infinity the solution is deterministic since the variance becomes zero.
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Fig shows the optical photomicrographs
2018-11-12
Fig. 11 shows the optical photomicrographs of shank portion of the failed shear screw showing crack initiation near the thread root (Fig. 11(a)). Fig. 11(b) shows the morphology of cracks with extensive branching that has initiated from a pit. Fig. 12(a) and b show the scanning pituitary adenylate c
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The projectiles were flat ended cylinders
2018-11-12
The projectiles were flat-ended cylinders made of a sintered tungsten alloy, Y925 from Kennametal Hertel AG [25]. Material data for the projectile are given in Table 3. The target confinement consisted of a steel tube (Böhler W725, Poisson\'s ratio and Young\'s modulus ). The external diameter of
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Introduction The possibility that firms can develop
2018-11-12
Introduction The possibility that firms can develop a competitive edge over rivals by investing in social responsibility has been made increasingly likely over recent years by changes in investors׳ behavior and attitudes towards the society (Graves & Waddock, 1994; Saleh, Zulkifli, & Muhamad, 2010;
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Introduction Entrepreneurial activities have been studied an
2018-11-12
Introduction Entrepreneurial activities have been studied and explained by prominent researchers making the notion even more (e.g., Baron & Ward, 2004; Markman & Baron, 2003; Mitchell et al., 2004). According to Schumpeter (1934),Kirzner (1973), an entrepreneur׳s role can be explained as an innovat
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Xi di is one of the
2018-11-12
Xi-di is one of the most famous ancient villages (Figure 1) in China, with a long history tracing back to the Song dynasty (A.D. 960–1279). The development of the village occurred during the period of the Ming dynasty, followed by prosperity in early Qing dynasty and downfall afterwards. More recent
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br Conclusion A message easily decoded by a medieval
2018-11-12
Conclusion A message easily decoded by a medieval person is possibly inaccessible to a modern person because even though we can always claim that a certain meaning behind all the historical monuments remain, we can no longer assure which meaning was retained. Similar to certain verbal languages t
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In the context of Christian inculturation
2018-11-12
In the context of Christian inculturation, the Xianxian-Daming handbook must be considered from two architectural points of view: Mifepristone and construction. About style, the handbook expresses a resistance of the ‘old school’ and missionaries such as Alphonse De Moerloose against the Sino-Chris
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