• When the analysis was matching with propensity score OS was

  2019-05-16

  

  When the analysis was matching with propensity score, OS was still significantly longer in JAK2+ patients (median not reached versus 73 months, p=.031) whereas JAK2 status had no significant prognostic value for OS in IPSS intermediate-2 and high patients (p=.18). Discussion In this series, whic

• On Aug WHO quietly released a

  2019-05-16

  

  On Aug 23, WHO quietly released a report that should be essential reading for all. Coming 15 years after the Abuja Declaration by African governments to commit to spending 15% of annual domestic budgets on health, concludes with a stark analysis: “For every US$100 that goes into state coffers in Af

• br Interpretation of identified genetic

  2019-05-16

  

  Interpretation of identified genetic variants and genetic counseling Although the current expert consensus statement recommends that comprehensive or BrS1 (SCN5A) targeted BrS genetic testing can be useful for genetic testing [63], not all the published SCN5A mutations in BrS have been subjected

• The exact location of the

  2019-05-16

  

  The exact location of the APs within the cusps is difficult to determine. The majority of studies used coronary angiography, and less commonly electroanatomical mapping. The morphology of local atrial and ventricular electrograms may be additionally used [1,2]. Mapping within the RCC typically shows

• br In their Comment on the use of antenatal

  2019-05-16

  

  In their Comment on the use of antenatal corticosteroids to reduce preterm infant deaths, Kishwar Azad and Anthony Costello advise “extreme caution” before scale-up in low-income settings. They emphasise maternal sepsis as a concern but cite only one trial in which dexamethasone resulted in a sign

• Go 6976 br Conclusion br Financial support

  2019-05-15

  

  Conclusion Financial support This research was supported by a grant from the ׳Gerencia de Salud, Consejería de Sanidad, Junta de Castilla y Leon׳ [GRS 308/A/08] and ‘Caja Burgos Foundation’ [Convocatoria 2007].The funding organization had no involvement in the study. Clinical trial registra

• Unfortunately no trends in retention in

  2019-05-15

  

  Unfortunately, no trends in retention in care were presented by Nsanzimana and colleagues, and the method used to estimate life expectancy—the abridged life table method—is not well suited to answering questions about trends in quality of care, because it pyk2 inhibitor allows little scope for multi

• Ser entonces la fotograf a

  2019-05-15

  

  Será entonces la fotografía la Marcha de los claveles rojos la consolidación del objetivo estético de Calanchina. Dicha imagen fue tomada en blanco y negro y Process Measures el instante justo donde un centenar de hombres y mujeres, reunidos frente al edificio de la Policía Nacional de Guatemala,

• La categorizaci n propuesta por

  2019-05-15

  

  La categorización propuesta por Margaret Randall es mucho más simple, puesto que distingue tan sólo entre aquellos testimonios en sí de los testimonios para sí. Christina Dupláa analiza tal distinción: Como puede verse, la clasificación es bastante difusa, ya que en la primera categoría se consider

• The Zika virus epidemic is spreading countries are now repor

  2019-05-15

  

  The Zika virus epidemic is spreading: 63 countries are now reporting transmission, over 1500 cases of related microcephaly or CNS malformations have been confirmed this year, and knowledge on the disease is advancing slowly. Adding to the tension around Zika, at the epicentre of the outbreak, Brazil

• As Table shows all guidelines recommend OACs for patients

  2019-05-15

  

  As Table 2 shows, all guidelines recommend OACs for patients with a CHADS2 score of ≥2, whereas recommendations for low-risk patients with a CHADS2 score of 0/1 differ slightly across guidelines. Evidence indicating that novel OACs decrease the risk of ICH by half as compared with warfarin has affec

• One day post implant the chest X

  2019-05-15

  

  One day post-implant, the chest X-ray showed the pacemaker lead in place within the RV (Fig. 1b, thick white arrow) with appropriate slack (thin black arrow). The pacemaker parameters were satisfactory and the patient was discharged home on the same day. Two weeks after implantation, after returnin

• In order to treat metastatic bone disease

  2019-05-15

  

  In order to treat metastatic bone disease effectively all steps involved in the metastatic cascade need to be taken into account as for example the interactions between primary and secondary sites, tumour cell–bone cell cross talk and osteomimicri [8]. Therefore, concomitant targeting of both the tu

• br Methods br Results br

  2019-05-15

  

  Methods Results Discussion The results of this study demonstrate that (1) low-dose landiolol (0.5μgkg−1min−1) prevent heart rate elevation after AF ablation; (2) prophylactic administration of low-dose landiolol successfully prevented immediate AF recurrence within 3d after AF ablation with

• br Conflict of interest br Acknowledgment br Introduction Th

  2019-05-15

  

  Conflict of interest Acknowledgment Introduction The majority of clot embolisms associated with atrial fibrillation (AF) are from the left atrial appendage (LAA). Before cardioversion or catheter ablation, clot formation needs to be ruled out traditionally using transesophageal echocardiogr

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