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It is interesting that OB
2018-10-31
It is interesting that OB neurons produced from the transient Gli1-enriched subcallosal domain in juvenile mice mostly corresponded to sGCs, when they were derived from a region with active SHH signaling. It is possible that the relative levels of SHH signaling are adjusted in different domains. The
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Our study showed that neurite length and the ratio
2018-10-31
Our study showed that neurite length and the ratio of apoptotic SB 203580 in FALS- and FUSH517D/H517D iPSC-derived neurons were the same as in control motor neurons. With several stresses especially in glutamate treatment, however, FALS- and FUSH517D/H517D HB9-positive motor neurons exhibited short
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This has important implications for competitive transplantat
2018-10-31
This has important implications for competitive transplantation experiments. Because they have the same reconstitution potential, modified HSPCs from any C57BL/6N or C57BL/6J strain can be directed compared with our CD45.1STEM strain without an additional control group. This contrasts with the situa
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Small conductance calcium activated potassium channels SK
2018-10-30
Small-conductance calcium-activated potassium channels (SK channels) are known to be involved in controlling the pacemaking activity of PCs [8]. Activation of SK channels leads to afterhyperpolarization of the cell membrane, maintaining regular vegfr inhibitor generation and suppressing the PC firin
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orthopox br Assuming R R R the difference in distances
2018-10-30
Assuming (R1+R2)≈2R, the difference in distances travelled is The discrepancy in ΔR between the approximate and real cases is 2h1/R and can be neglected if it is much smaller than π. The concept of parallel rays is applicable if Both SPLLS and EDCLLS are used in combination with a remote con
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br Methods A scoping review determines the extent range
2018-10-30
Methods A scoping review determines the extent, range and nature of any research activity, making it a more suitable approach than a systematic review for this research question (Arksey & O’Malley, 2005; Levac, Colquhoun, & O’Brien, 2010). Given the complexity of the review design, a detailed pro
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Then we demonstrated the major role of frailty
2018-10-30
Then, we demonstrated the major role of frailty in the relationship between falling and social participation. The construction of the frailty daunorubicin (Fried et al., 2001; Santos-Eggimann et al., 2009) was based on its physical component. In this manner, frailty and falling were very close cons
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br Methods br Results In there
2018-10-30
Methods Results In 1860 there were 1100 counties within the boundaries of states legally permitting slavery (Upper South: 621; Deep South: 479), and in 2010 these same states consisted of 1,347 counties or county equivalents (716 and 624 for the Upper and Deep South, respectively). Spatial in
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br Acknowledgements This work was supported
2018-10-30
Acknowledgements This work was supported by NIH grants 1R01MD006064 and 1R21HD066312 (Dr. Osypuk, PI), and the Minnesota Population Center grant P2C HD041023. Funders did not have any role in design or conduct of the study; collection, management, analysis, and interpretation of the data; or prep
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En suma desde la poca del keynesianismo surgieron interrogan
2018-10-30
En suma, desde la época del keynesianismo surgieron interrogantes sobre la liberación de mercados –validados por la experiencia de los últimos años– que se condensan en intensas tensiones entre las exigencias del comercio globalizado y la autonomía económica de los países para satisfacer objetivos p
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br Building measures that are representative of the panel of
2018-10-30
Building measures that are representative of the panel of inflation forecasts Aggregate measures such as the mean, median and standard deviation of the expectations panel surveyed by the Central Bank of Brazil, and others derived from these three, are reported daily at the central bank\'s website
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Kearney and Levine present a detailed survey of
2018-10-30
Kearney and Levine (2012) present a detailed survey of teenage childbearing in the US. The main conclusion is that both actual and perceived lack of economic opportunities influence early motherhood. After these factors have been taken into account, teenage motherhood does not appear to cause additi
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Increasing productivity reducing costs and the expansion of
2018-10-30
Increasing productivity, reducing costs, and the expansion of the complexity and value of the offered products (best price/performance ratio) was more pronounced in leading companies because of the adoption of organizational changes associated with headcount sulfanilamide to rationalize production;
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The levels of LRG have been
2018-10-30
The levels of LRG1 have been shown to be elevated in the serum and urinary exosomes of lung cancer patients (Li et al., 2011; Liu et al., 2012) with this protein also being identified in lung tumour tissue. The role of LRG1 is not fully understood, although it is of interest due to its role in angio
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This interpretation is consistent with results from animal
2018-10-30
This interpretation is consistent with results from animal studies. In mice, as in humans, enhanced systemic inflammation is associated with accelerated ageing and increased mortality risk (Osorio et al., 2012; Kawahara et al., 2009; Tilstra et al., 2012; Caballero et al., 2009). Importantly, system
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