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br Discussion CML was the first malignancy to be linked
2019-06-13
Discussion CML was the first malignancy to be linked to a clear genetic abnormality, the Philadelphia chromosome. This chromosomal abnormality is so named because of the city in which it was first discovered and described in 1960 by Peter Nowell and David Hungerford [1]. The fusion protein result
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ligand gated br Clinical evidence to support
2019-06-13
Clinical evidence to support that PES predicts cardiac events in BS Brugada et al. were the first to propose that inducibility of sustained ventricular arrhythmias with PES is useful to identify patients who are at high risk of SCD [3]. During follow-up of patients with spontaneous type 1 Brugada
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br Discussion Prehabilitation is a program to
2019-06-13
Discussion “Prehabilitation” is a program to enhance functional capacity and psychological health to enable patients to withstand an upcoming stressor, e.g. surgery. It is intended to reduce treatment-related morbidity and/or mortality, to decrease length of hospital stay and/or re-admission, and
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Programmed death ligand PD L expression is a characteristic
2019-06-13
Programmed death ligand 1 (PD-L1) expression is a characteristic feature of EBV-associated malignancies. Research has shown that an increase of PD-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma. Preliminary data from a phase Ib study, KEYNOTE-028, showe
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The results of our initial cross sectional
2019-06-13
The results of our initial cross-sectional analyses assessing the clinical characteristics of the patients participating in ASSAF-K are shown in Table 1. As compared with the “Fushimi AF Registry,” considered a representative Japanese AF registry with an initial registration of 3183 patients [28], t
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Un peculiar texto de Borges enumera al interior de
2019-06-13
Un peculiar texto de Borges enumera, al interior de su relato, interesantes ejemplos de varias categorías pertenecientes al idioma propuesto por John Wil-kins —un sabio inglés del siglo — cuyo objetivo fue diseñar un lenguaje mucho más completo, abarcador e incluso preciso, en sus descripciones del
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Ulises criollo pertenecer a a
2019-06-13
Ulises criollo pertenecería UNC0638 lo que en inglés se cataloga como nonfiction prose. Al escribirlo la principal intención de Vasconcelos no fue la de narrar en el sentido ficcional (imaginativo, desinteresado, novelesco) sino interpretar, sentar una comprensión de su época y de su país a partir d
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En Latinoam rica donde se presentan intentos de
2019-06-13
En Latinoamérica, donde se presentan intentos de fundar identidades regionales o nacionales que ejerzan contrapeso order VX-765 los embates de homogeneización cultural, han aparecido diversos criterios relacionados con políticas universalistas o con el cosmopolitismo. Estos criterios sustentaron inf
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Preventive chemotherapy for schistosomiasis is rapidly scali
2019-06-12
Preventive chemotherapy for schistosomiasis is rapidly scaling up worldwide. The global coverage that was less than 10% in 2010 is now higher than 30%, however, the main limitation for the scaling up is the availability of donated drug. In school age children, the age group for which praziquantel is
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br Arrhythmogenic right ventricular cardiomyopathy ARVC an i
2019-06-12
Arrhythmogenic right ventricular cardiomyopathy (ARVC), an inherited heart muscle disease, is associated with a high risk of arrhythmias and sudden cardiac death . It is characterized primarily by fibrofatty replacement of the right ventricular myocardium, which is often accompanied by subsequent
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caspofungin Conflicts of interest br Acknowledgments This
2019-06-12
Conflicts of interest Acknowledgments This article was supported by grants from the Ministry of Science and Technology, Executive Yuan (MOST 103-2314-B-010-043-MY3), and Taipei Veterans General Hospital (V103C-112; V104C-095; and V105C-096). We also appreciate the Clinical Research Core Laborato
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With respect to the ST
2019-06-12
With respect to the ST elevation in the precordial lead, Antzelevitch et al. demonstrated that this can be an molecular weight calculator of early repolarization or J-wave caused by transient outward current (Ito)-mediated transmural differences in the early phases of the action potential. BS is an
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It is noteworthy that even with low tumor burden
2019-06-12
It is noteworthy that, even with low tumor burden in these patients following CR, peak value at CR status is still a useful indicator for OS, both in the whole cohort, and more importantly, in the intermediate-risk subgroup. Slope is mainly determined by tissue vascularization and perfusion, but cap
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br The role of other bone marrow
2019-06-12
The role of other bone marrow cells in metastatic cancer growth Other cell types also that take part in the regulation of the bone microenvironment, including myeloid and immune cells (T cells), platelets, bone marrow endothelial and haematopoietic cells, as well as bone marrow-derived mesenchyma
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Amongst other anti arrhythmic medications disopyramide class
2019-06-12
Amongst other anti-arrhythmic medications, disopyramide (class 1A AAM) has anticholinergic side effects such as dry mouth, urinary hesitancy, constipation and exacerbation of conditions like glaucoma and myasthenia gravis. Disopyramide acts by targeting the fast sodium glucose transport proteins in
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